The drug is used to control high lipid levels and commonly used in cardiovascular disease.
This drug is HMG-CoA Reductase inhibitor (statins) , acts by inhibiting the conversion of HMG-CoA (3-Hydro-3-methyl glutaryl coenzyme A) to mevalonate by enzyme HMG-CoA reductase.
Hence it reduces CH Synthesis by 20-25%.
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Chemical formula – C33H35 FN2O5
Drug class - HMG-CoA Reductase inhibitors(statins)
Trade name - Lipitor
Uses -
Used to control abnormal lipid levels in blood that is dyslipidemia.(hyperlipidemia and hypercholesterolemia).
Statins are first line of treatment for cardiovascular disease.( prevention of heart attack)
Advantage -
More potent than other statins
Highest LDL-CH lowering efficacy.
Half life is more than other statins
Prevent cardio vascular disease.
Side effects
- Joint pain
- Loose stools
- Muscle pain
- Head ache, nausea
- Myopathy
- Rashes
- Bowel upset
