The drug is used to control high lipid levels and commonly used in cardiovascular disease.

This drug is HMG-CoA Reductase inhibitor (statins) , acts by inhibiting the conversion of HMG-CoA (3-Hydro-3-methyl glutaryl coenzyme A) to mevalonate by enzyme HMG-CoA reductase.

Hence it reduces CH Synthesis by 20-25%.

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  • Chemical formula  – C33H35 FN2O5

    Drug class - HMG-CoA Reductase inhibitors(statins)

    Trade name - Lipitor

    Uses -

    Used to control abnormal lipid levels in blood that is dyslipidemia.(hyperlipidemia and hypercholesterolemia).

    Statins are first line of treatment for cardiovascular disease.( prevention of heart attack)

     

    Advantage -

    More potent than other statins

    Highest LDL-CH lowering efficacy.

    Half life is more than other statins

    Prevent cardio vascular disease.

    Side effects

    • Joint pain
    • Loose stools
    • Muscle pain
    • Head ache, nausea
    • Myopathy
    • Rashes
    • Bowel upset